Freezing Codex (tank)
Tank: Pull him away from the Freezing Codex book-storm circling him at the start of the fight. It is smaller and less of a problem away from where it first appears.
Hard Mode: Raise the Challenge Banner and interact with 'Riftmaster Naqri's Memoirs' on the desk/table directly to the left of the banner to burn it before entering the main boss platform (Veteran only; achievements: Harsh Edit / Literate Combatant).
Tank: Pull him away from the Freezing Codex book-storm circling him at the start of the fight. It is smaller and less of a problem away from where it first appears.
All: Watch your footing around the ice bolts his circling books periodically fire in several directions. They are small ground effects individually, but being hit by several in quick succession can kill you.
Dps: Red rune active: a projectile add spawns that must be interrupted immediately before it damages the group.
All: Green rune active: a homing AoE spawns beneath players and moves; block through it to reduce incoming damage.
All: White (or Yellow) rune active: ghosts spawn that channel a charged heavy attack ignoring dodge rolls. You must hold block.
Dps: At 85% (White), 55% (Green), and 35% health (Red), a floating book appears with a colored rune and periodically fires colored bolts toward two bookcases around the room. One DPS should break off alone (bring a shield or self-heal) to find and destroy both Hidden Codex books each time this happens. The active rune's attack repeats and deals more damage the longer it is left up. With enough group damage you may be able to skip hunting for the final set at 35% and focus the boss down instead.
Tank: Stand in each small green Unstable Literature circle before it explodes to soak it. If nobody does, it deals heavy damage to the whole group and can cause a wipe.
Tank: Hard Mode only: two Unstable Literature circles spawn at once. Take one yourself.
Healer: Hard Mode only: two Unstable Literature circles spawn at once. Take the second one, since the DPS are likely busy hunting Hidden Codex books.
All: Kill each Cartoklept you find quickly. They fight back but try to flee, and an escapee teleports to one of the dungeon's other spawn points (including the Deadlands and Spiral Skein sections), keeping whatever damage you had already done to it. Each kill drops a character-bound Vault Key.
All: Locked within the Vault of Scrivener's Hall. Guaranteed to spawn only after using Cartoklept Scamp keys to open at least 20 chests (Small on Normal, Large on Veteran; group-wide pool) inside the vault map. She teleports around the room like a Cartoklept while fighting back aggressively.
Hard Mode: Activate the Challenge Banner near the boss before engaging (Veteran only; achievement: Dousing Exterminator).
Tank: Keep him near the arena's edge. Every time he burrows and resurfaces elsewhere he leaves a permanent lava pool, and holding him against the wall makes new pools overlap the wall and old pools instead of taking fresh floor space.
All: Lava pools are permanent for the rest of the fight. Do not back into an old one.
All: If a laser locks onto you (two players get one at a time), kite it for a few seconds without crossing another kiting player's path.
All: Hard Mode only: the laser locks onto all four players at once instead of two. Plan your kiting lane in advance so you do not cross anyone else's.
Tank: Vile Secretions is a devastating frontal poison cone that can kill anyone but the tank. Hold aggro and keep him turned away from the group at all times.
All: Step on the larvae he scatters around the room as soon as you see them. This kills them outright before they can grow into flying Evolved Broodling adds.
Dps: Interrupt any Evolved Broodling that starts channeling. Left alone it deals a heavy damage-over-time effect to the whole group.
All: About halfway through the fight he burrows to the room's center and a large effect expands to cover roughly 90% of the room before pulling everyone toward the middle. Get to the outer edge before it finishes expanding. Caught inside it, you are pulled all the way in and killed; clear in time, you are only pulled partway, but make sure there is no lava pool between you and the center or you are dragged through it.
Tank: Hard Mode only: an Iron Atronach spawns at 40% and 20% health. Taunt it immediately. A confident tank and strong group damage can sometimes ignore one or both and push through instead.
All: Hard Mode only: the Green Bugs present on every difficulty (harmless fire bolts on Normal and Veteran) instead grow into full adds if left alone. Run over them the moment you see them.
Hard Mode: Activate the Challenge Banner near the boss before engaging (Veteran only; achievement: Inflammable).
Tank: Hold aggro on Lamikhai, the giant spider you fight first, and block. She deals heavy damage.
Tank: When Lamikhai glows red she is enraged and deals more damage. Lure her into the ice area the friendly NPC drops to freeze her and clear the enrage.
Dps: From the second area onward, kill the small spider Lamikhai spawns immediately. Its web pulls a targeted player in, and reaching the spider is instantly lethal.
All: A red rune over your head marks you for a Fire Meteor. Move to a new spot before it lands, since it leaves a permanent fire area where it hits. Drop it near the room's edge, away from the exit you will need to sprint through later.
All: At each area-transition health threshold she flees and the room starts filling with a lethal effect. Run through the gate that opens immediately; do not linger.
All: If an expanding effect is placed on you, stay inside it until it explodes. Leaving early is a guaranteed kill; staying put is safe.
All: Her mark leaves a permanent ground effect where it expires on you. Let it expire near the room's edge, not the middle, to keep the arena usable.
All: If a circle appears under you, stay inside it until it disappears, and do not step into anyone else's circle; it is heavy damage or death for both of you.
Tank: Hold aggro through her flamethrower channel and keep her facing away from the group.
Dps: In the fight's final area, destroy the glowing meteor orbs that land before they explode. An intact one knocks the group back and deals heavy damage, risking a wipe.